The University Hospital of the Ludwig-Maximilians-University Munich consists of the campus Großhadern and the Campus Innenstadt. It is one of the largest general hospitals in Germany and Europe. Over the last years, optimal technical conditions have been created at the Department of Radiation Oncology to address the tasks within the SPARTA project. The clinic has three IMRT/IGRT-capable accelerators: two LINACS with VMAT and kV cone-beam CT, as well as one LINAC with MV cone-beam CT. There is access to all relevant imaging modalities, including PET-CT and PET-MR. Moreover, the University Hospital has a broad expertise in the field of clinical IMRT/IGRT implementation and the application of biological models in the context of radiotherapy treatment planning. The clinic is working in close collaboration with the Chair of Medical Physics of the Ludwig-Maximilians-University, established in 2012. The extensive expertise and close collaboration in the areas of medicine and medical physics are used within the SPARTA project to foster work on adaptive, image-guided radiotherapy for head and neck cancer with photons an protons.