Monitoring of interfractional motion in respiratory-gated radiotherapy

As compared to conventional techniques, respiratory-gated radiotherapy of lung tumors irradiated less normal tissue and thus reduces the risk of side effects. Based on an anthropomorphic dynamic lung phantom, a method was developed to simulate the workflow of a respiratory-gated treatment and to verify the three-dimensional dose distribution. Due to its realistic soft-tissue contrast, the phantom may be used to validate image-guided procedures in radiotherapy.


The open source software library RT-Toolbox is the penknife for quantitative analysis of RT data sets. It was developed and enhanced during the SPARTA project and its predecessors. The RT-Toolbox supports the full range of radiotherapy evaluation. Tools such as DVH calculation, arithmetic operations on dose distributions and structure relationship analysis are provided as a basis for further calculations. Dose comparison indices are determined from dose distributions and DVHs. 


AVID is a software framework for automated analysis of large patient collections. It was developed within SPARTA. Previously defined workflows define the analysis goal (e.g. retrospective dose analysis). AVID connects different within SPARTA developed tools and enables an automation that is new and innovative in the RT context. Only the analysis of large patient collections can lead to new insights and a better therapy. An example that was done is an uncertainty analysis that evaluates the effects of registration errors to the patient dose (see diagram).